What affects global public opinion about U.S. foreign policy? The authors examine this question using a cross-national survey conducted during and immediately after the 2001 U.S.-led war in Afghanistan. They propose three models of global public opinion - interests, socialization, and influence - and discuss their empirical validity. Socialization variables (e.g., Muslim population and past terrorist incidents) tend to exhibit significant effects. A variable measuring shared security interests, North Atlantic Treaty Organization membership, has significant effects in favor of U.S. policy, but other mutual defense pacts with the U.S. have a backlash effect. Shared economic interests, represented by levels of trade, also have a positive influence. Variables measuring conflicting security interests as well as those measuring U.S. efforts to influence foreign public opinion have insignificant or weak effects.