InfiniCloud 2.0 is the world's first native InfiniBand High Performance Cloud distributed across four continents, spanning Asia, Australia, Europe and North America. The project provides researchers with instant access to computational, storage and network resources distributed around the globe. These resources are then used to build a geographically distributed, virtual supercomputer, complete with globally-accessible parallel file system and job scheduling. This paper describes the high level design and the implementation details of InfiniCloud 2.0. Two example applications types, a gene sequencing pipeline and plasma physics simulation code were chosen to demonstrate the system's capabilities.