This paper provides a preliminary overview of research on organized crime in Asia drawing on selected papers from a symposium held at the National University of Singapore in June 2007. We draw on these contributions to emphasize the enterprise nature of organized crime and the common problems encountered by law enforcement in controlling and preventing the many harms inflicted by serious criminal activity. Recent attempts to address the changing character and forms of transnational organized crime, especially through the strengthening of mutual legal assistance by regional bodies such as ASEAN, are noted. These measures have yet to develop into the cross-border institutional frameworks now found in Europe, and the level of effective co-operation can only continue to improve. Countering organized crime in Asia also faces additional difficulties arising from the cultural diversity, relative weakness of law enforcement in some states and the lack of common strategies in respect to illicit markets.