This paper provides an overview and analysis of wine regulations in an international and historical comparative perspective. Wine is an excellent sector to study government interventions because for centuries wine markets have been subject to many government regulations that differ greatly within and between countries. Wine consumption taxes, for example, range from zero in some countries to more than 100% in others. The European Union has extensive quantity and quality regulations for wine, while other major producers such as Australia and the United States are much less regulated. After a general overview of current regulations and historical evolutions, we analyze three key wine regulations in more detail: consumption taxes, planting rights, and geographical indications. Most wine regulations reveal a tension between the public interest and vested private interests.